Pharmaceutical formulations for dry powder inhalers in the...

A - Human Necessities – 61 – K

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Details

A61K 31/573 (2006.01) A61K 9/14 (2006.01) A61K 9/72 (2006.01) A61K 31/167 (2006.01)

Patent

CA 2406119

The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of active ingredients into the low respiratory tract of patients suffering of pulmonary diseases such as asthma. In particular, the invention provides a formulation to be administered as dry powder for inhalation freely flowable, which can be produced in a simple way, physically and chemically stable and able of delivering either accurate doses and high fine particle fraction of low strength active ingredients by using a high- or medium resistance device.

L'invention concerne une formulation pour inhalation administrée sous forme de poudre sèche, appropriée à la distribution efficace d'ingrédients actifs dans les voies respiratoires inférieures d'un patient souffrant de maladies pulmonaires telles que l'asthme. Ladite invention concerne, en particulier, une formulation pour inhalation administrée sous forme de poudre s'écoulant librement, qui peut être produite de manière simple, physiquement et chimiquement stable, et capable de distribuer des doses précises et une fraction élevée de particules fines d'ingrédients actifs à faible résistance à l'aide d'un dispositif à résistance élevée ou moyenne.

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