Pharmaceutical formulations of bisphosphonates

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61K 31/663 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2548363

A pharmaceutical formulation comprising an oral dosage form containing a bisphosphonic acid or a salt thereof and an inactive ingredient selected from: an ester of a medium chain fatty acid, or a lipophilic polyethylene glycol ester, said inactive ingredient having a hydrophilic lipophilic balance (HLB) of from about 1 to about 30.

L'invention concerne une formulation pharmaceutique comprenant une forme posologique orale contenant un acide bisphosphonique ou un sel de celui-ci et un ingrédient inactif choisi dans un ester d'un acide gras à chaîne moyenne, ou un ester glycol polyéthylène lipophile, ledit ingrédient inactif présentant un rapport hydrophile-lipophile (HLB) compris entre environ 1 et environ 30.

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