Pharmaceutical formulations of cefaclor

A - Human Necessities – 61 – K

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A61K 31/54 (2006.01) A61K 9/00 (2006.01) A61K 31/545 (2006.01)

Patent

CA 2158511

Pharmaceutical formulations of cefaclor, suitable for the direct-compression manufacture of dispersible tablets, containing the antibiotic cefaclor in an amount between 35% and 50% by weight of the total weight of the formulation, along withsuitable excipients and coadjuvants selected from disintegrators, diluents, lubricants, antiadherents, sweeteners, fragrances and, optionally, flavorings, opacifiers and colorants. Said formulations are suitable for the manufacture of dispersible tablets which disintegrate in less than three minutes in water at 19° - 21°C, and are suitable for the treatment of infections caused by bacteria strains sensitive to cefaclor.

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