Pharmaceutical formulations of highly lipophilic...

Details Pharmaceutical formulations of highly lipophilic... Pharmaceutical formulations of highly lipophilic...

A - Human Necessities

61

K

A61K 31/47 (2006.01) A61K 9/107 (2006.01) A61K 31/4745 (2006.01) A61K 47/00 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61K 47/28 (2006.01)

Patent

CA 2223259

A pharmaceutical formulation, as a solution or suspension of pH from 2 to 6, of camptothecin or a lipophilic camptothecin derivative, having a water solubility of less than 5 micrograms/ml, in N-methylpyrrolidin- 2-one.

Cette invention concerne une formulation pharmaceutique à base de camptothécine ou d'un dérivé lipophile de la camptothécine ayant une solubilité dans l'eau inférieure à 5 mg/ml, cette formulation se présentant sous la forme d'une solution ou d'une suspension à PH compris entre 2 et 6, dans un solvant à base de N-méthylpyrrolidin-2-one.

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