Pharmaceutical formulations of loratadine for encapsulation...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/14 (2006.01) A61K 9/48 (2006.01) A61K 31/4545 (2006.01)

Patent

CA 2690490

This invention relates to a loratadine formulation suitable for encapsulation into a soft gel capsule dosage unit by increasing the stability, concentration, and bioavailability of loratadine. The highly concentrated formulation of this invention permits a reduction in the fill volume or dosage unit size, or an increase in concentration of the active pharmaceutical ingredient per dosage form. The invention also relates to a formulation of optimal stability suitable for supporting a fill composition compatible with the soft gel capsule dosage unit.

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