Pharmaceutical formulations of taxanes

Details Pharmaceutical formulations of taxanes Pharmaceutical formulations of taxanes

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2321826

A pharmaceutical formulation of a taxane antineoplastic agent, particularly paclitaxel or docetaxel or a pharmaceutically acceptable salt thereof, and N-methylpyrrolidin-2-one (NMP), and/or Dimethylacetamide (DMA), and/or Dimethylisosorbide (DMI). The formulation may include other excipients and/or diluents, and is suitable for administration to patients with cancer.

L'invention concerne une formulation pharmaceutique comprenant un agent antinéoplasique à base de taxanes, notamment le paclitaxel ou le docétaxel ou un de leurs sels pharmaceutiquement acceptables, ainsi que N-méthyl-pyrrolidin-2-one (NMP) et/ou diméthylacétamide (DMA) et/ou diméthylisosorbide (DMI). Cette formulation peut contenir d'autres excipients et/ou diluants, et convient à l'administration à des patients atteints du cancer.

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