Pharmaceutical formulations, their preparation and use

A - Human Necessities – 61 – K

Patent

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A61K 31/485 (2006.01) A61K 9/20 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2156768

Formulations of ibuprofen and codeine (or a pharmaceutically acceptable salt of either of them) include a carrier comprising a disintegrant, diluent, and a lubricant substantially free from stearic acid and stearate ions and selected from hydrogenated vegetable oils. Preferred formulations are directly-compressed tablets which are useful for treating pain and inflammation.

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