C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/10 (2006.01) A61K 31/397 (2006.01) A61K 31/4025 (2006.01) A61K 31/41 (2006.01) A61K 31/422 (2006.01) A61K 31/4523 (2006.01) A61P 9/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2754384
The present invention relates to novel azetidinone-containing compounds having a novel side-chain which is at-tached to the aryl ring at C4 via a C-C bond and comprises a 3,3- disubstituted oxetane ring and a polar group A, and which are useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels.
La présente invention concerne de nouveaux composés contenant de l'azétidinone qui présentent une nouvelle chaîne latérale qui est attachée au noyau aryle en C4 par l'intermédiaire d'une liaison C-C et qui comporte un noyau oxétane 3,3-disubstitué et un groupe polaire A, et qui sont utiles dans le traitement et la prévention de l'athérosclérose et pour la réduction des taux de cholestérol.
Barbaras Damien
Carreira Erick
Fessard Thomas
Li Dong-Bo
Wolfrum Susanne
Cassan Maclean
Lipideon Biotechnology Ag
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