Pharmaceutical manufacturing process

A - Human Necessities – 61 – K

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Details

A61K 9/10 (2006.01) A61K 9/72 (2006.01) A61K 31/573 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2587393

The present invention provides a method for preparing a sterile suspension of a glucocorticosteroid. The glucocorticosteroids used in the invention are preferably anti~inflammatory glucocorticosteroids. By making the last stage of product preparation be the sterilization process, the potential for contamination during manufacture and heat degradation of products is greatly reduced.

L'invention concerne un procédé de fabrication d'une suspension stérile d'un glucocorticostéroïde. Les glucocorticostéroïdes utilisés dans l'invention sont de préférence des glucocorticostéroïdes anti-inflammatoires. La dernière étape de préparation du produit étant le procédé de stérilisation, le risque de contamination pendant la fabrication et de dégradation par la chaleur des produits est sensiblement réduit.

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