Pharmaceutical metered dose inhaler and methods relating...

A - Human Necessities – 61 – M

Patent

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Details

A61M 15/00 (2006.01) A61M 11/00 (2006.01)

Patent

CA 2536876

Metering valves for use in a metered dose inhaler that include a valve body, a first stem seal including a first elastomeric material, a second stem seal including a second elastomeric material different from the first elastomeric material, and a valve stem slidably engaged with at least one of the first stem seal and the second stem seal as well as sealed containers configured to contain an aerosol pharmaceutical formulation that include a container having an opening therein, a cap covering the opening in the container, a metering valve adjacent the cap, and a cap seal positioned between the cap and the container to provide a sealed container where the metering valve include at least one stem seal that includes a first elastomeric material, and the cap seal includes a second elastomeric material different from the first elastomeric material are described.

L'invention concerne des valves doseuses à utiliser dans un aérosol-doseur qui comprennent : un corps de valve ; un premier joint de tige qui comprend un premier matériau élastomère ; un deuxième joint de tige qui comprend un deuxième matériau élastomère différent du premier matériau élastomère ; et une tige de valve en contact coulissant avec au moins le premier ou le deuxième joint de tige. L'invention concerne également des récipients étanches conçus pour contenir une formulation pharmaceutique d'aérosol qui comprennent : un récipient dans lequel se situe une ouverture ; un couvercle recouvrant cette ouverture ; une valve doseuse montée adjacente au couvercle ; et un joint de couvercle positionné entre le couvercle et le récipient permettant d'étanchéifier le récipient, la valve doseuse comprenant au moins un joint de tige qui comporte une premier matériau élastomère, et le joint de couvercle comportant un deuxième matériau élastomère différent du premier matériau élastomère.

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