C - Chemistry – Metallurgy – 08 – K
Patent
C - Chemistry, Metallurgy
08
K
C08K 5/09 (2006.01) C08F 6/00 (2006.01) C08K 5/13 (2006.01)
Patent
CA 2534985
Methods of preparing elastomeric gasket materials for use in metered dose inhalers that include contacting an elastomeric gasket material to be used in a metered dose inhaler, which gasket material comprises one or more extractable compounds, with a solution comprising an organic solvent under conditions sufficient to extract at least a portion of at least one of the one or more extractable compounds from the elastomeric gasket material are described. Sealing gaskets made by such methods as well as metering valves, metered dose inhalers, and drug products that include such gaskets are also described.
L'invention concerne des procédés de préparation de matériaux de joint élastomères destinés à être employés dans des aérosols doseurs, consistant à mettre en contact un matériau de joint élastomère contenant un ou plusieurs composés extractibles, avec une solution contenant un solvant organique, dans des conditions permettant l'extraction d'au moins une partie d'au moins un desdits composés extractibles du matériau joint élastomère. L'invention concerne également des joints ainsi fabriqués, des valves de dosage, des aérosols doseurs, et des produits pharmaceutiques contenant de tels joints.
Miller John Francis
Sommerville Mark Lee
Glaxo Group Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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