Pharmaceutical microspheres of valproic acid for oral...

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2267096

The invention concerns pharmaceutical microspheres containing as active principle a mixture of valproic acid and one of its pharmaceutically acceptable salts, associated with a matrix support selected among glycerol esters, hydrogenated oils, esterified polyethyleneglycols, waxes and their mixtures.

L'invention a pour objet des microsphères pharmaceutiques contenant, comme principe actif, un mélange d'acide valproïque et d'un de ses sels pharmaceutiquement acceptables, en association à un support matriciel choisi parmi des esters de glycérols, des huiles hydrogénées, des polyéthylèneglycols estérifiés, des cires et leurs mélanges.

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