Pharmaceutical preparation

A - Human Necessities – 61 – K

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Details

A61K 35/14 (2006.01) C12N 5/078 (2010.01)

Patent

CA 2747207

The present invention relates to a pharmaceutical preparation for treating an inflammatory condition, preferably a condition associated with ischemia comprising: a) a physiological solution comprising peripheral blood mononuclear cells (PBM--Cs) or a subset thereof, or b) a supernatant of the solution a), wherein the solution a) is obtainable by cultivating PBMCs or a subset thereof in a physiological solution free of PBMC-proliferating and PBMC- activating substances for at least 1 h.

La présente invention porte sur une préparation pharmaceutique destinée à traiter un état inflammatoire, de préférence un état associé à une ischémie, comprenant : a) une solution physiologique comprenant des cellules sanguines périphériques mononucléaires (PBMC) ou un sous-ensemble de celles-ci, ou b) un surnageant de la solution a), la solution a) pouvant être obtenue par culture des PBMC ou d'un sous-ensemble de celles-ci dans une solution physiologique exempte de substances faisant proliférer les PBMC et activant les PBMC pendant au moins 1 heure.

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