A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/66 (2006.01) A61K 31/663 (2006.01) A61K 47/38 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2301185
The object of the invention is a pharmaceutical preparation for oral use, especially a tablet, which as its active ingredient contains a pharmacologically acceptable salt of dichloromethylene bisphosphonic acid, i.e. a clodronate, especially disodium clodronate, and which as an excipient contains silicified microcrystalline cellulose. Further objects of the invention are a process for the manufacture of said pharmaceutical preparation, and the use of silicified microcrystalline cellulose for the manufacture of said pharmaceutical preparation.
Préparation pharmaceutique par voie orale, en particulier sous forme de comprimé, qui contient en tant que principe actif un sel acceptable sur le plan pharmaceutique de dichlorométhylène-acide biphosphonique, par ex. du clodronate, en particulier du clodronate disodique, et qui contient en tant qu'excipient de la cellulose microcristalline silicifiée. La présente invention concerne également un procédé de fabrication de ladite préparation pharmaceutique, et l'utilisation de cellulose microcristalline silicifiée pour la fabrication de ladite préparation pharmaceutique.
Lehtola Veli-Matti
Rantala Eeva-Maria Susanne
Rantala Pertti Tapani
Leiras Oy
Mccarthy Tetrault Llp
Schering Oy
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