A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/19 (2006.01) A61K 9/127 (2006.01) A61K 31/4045 (2006.01) A61K 31/416 (2006.01) A61K 38/13 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2288958
Lyophilized composition comprising trehalose and lipid liposomes in which a biologically-active principle has been incorporated, characterized in that the biologically-active principle is highly insoluble in water, the trehalose/lipid weight ratio is <= 1.5, and all of the trehalose was added to the outside of the liposomes already formed before lyophilization.
Cette composition lyophilisée comprend un tréhalose ainsi que des liposomes lipidiques dans lesquels on a incorporé un principe actif sur le plan biologique, et elle est caractérisée en ce que ce principe actif est essentiellement insoluble dans l'eau, en ce que le rapport pondéral tréhalose/lipide est </=1,5 et en ce que l'on a ajouté tout le tréhalose sur l'extérieur des liposomes déjà formés, avant lyophilisation.
Cavallo Giovanni
Marchitto Leonardo
Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a.
Riches Mckenzie & Herbert Llp
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