Pharmaceutical preparation comprising supernatant of blood...

A - Human Necessities – 61 – K

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A61K 35/14 (2006.01)

Patent

CA 2746862

The present invention relates to a topical pharmaceutical preparation for treating an inflammatory skin condition, preferably a condition associated with ischemia, comprising a supernatant of a physiological solution obtainable by cultivating peripheral blood mononuclear cells (PBMCs) or a subset thereof in a physiological solution free of PBMC-prolif erating and PBMC-activating substances for at least 1 h.

La présente invention concerne une préparation pharmaceutique topique destinée au traitement d'un état inflammatoire de la peau, de préférence un état associé à l'ischémie. Cette préparation comprend un surnageant d'une solution physiologique s'obtenant par culture, pendant au moins 1 heure, de cellules mononucléaires du sang périphérique ou "PBMC" (Peripheral Blood Mononuclear Cell) ou de l'un de leurs sous-ensembles, dans une solution physiologique exempte de substances faisant proliférer les PBMC ainsi que de substance activant les PBMC.

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