Pharmaceutical preparation for the diagnosis of helicobacter...

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01) A61K 9/30 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01) A61K 49/18 (2006.01) A61K 51/12 (2006.01)

Patent

CA 2408992

Preparations by which infection with H. pylori can be quickly detected while eliminating the effects of urease-producing bacteria occurring in organs other than the gastrointestinal tract (i.e., oral cavity, throat, etc.) without any fear of the detection of false positive. Namely, preparations for detecting infection with H. pylori by the urea expiration test wherein a core composition, which contains at least a C isotope-labeled urea, a filler and a lubricant at a definite ratio, is surface-coated with from 0.1 to 10% by weight, per 100% by weight of the core composition, of a coating.

L'invention porte sur des préparation permettant de détecter rapidement les infections par l'<i>Helicobacter pylori</i>, tout en éliminant les effets des bactéries productrices d'uréase dans des organes autres que le tube digestif (par exemple la bouche, la gorge, etc.) sans aucun risque de détection de faux positifs. Et notamment sur des préparation permettant de détecter les infections par l'<i>Helicobacter pylori</i>, par un test d'expiration de l'urée utilisant une composition granulaire comportant au moins de l'urée marqué par un isotope de C, une charge et un lubrifiant dans des proportions définies et munie d'un revêtement représentant de 0,1 à 10 % en poids des grains.

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