Pharmaceutical preparation with factor viii procoagulant...

Details Pharmaceutical preparation with factor viii procoagulant... Pharmaceutical preparation with factor viii procoagulant...

C - Chemistry, Metallurgy

07

K

C07K 14/755 (2006.01) A61K 38/37 (2006.01) C07K 1/22 (2006.01) C07K 16/36 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2205824

The invention is drawn to a stable pharmaceutical preparation containing a protein with factor VIII procoagulant activity and vWF binding activity, which protein has an amino acid sequence derived from the amino acid sequence of the factor VIII protein, comprising at least one mutation in at least one immunodominant region of factor VIII. Further, methods for producing such a stable pharmaceutical preparation and medical uses for such preparations are described.

L'invention porte sur une préparation pharmaceutique stable contenant une protéine ayant une activité coagulante du facteur VIII et une activité fixatrice de v-WF, laquelle protéine contient une séquence d'acide aminé dérivée de la séquence d'acide aminé de la protéine du facteur VIII, comportant au moins une mutation dans au moins une région immunodominante du facteur VIII. De plus, les méthodes qui permettent de produire une telle préparation pharmaceutique stable ainsi que les indications médicales de ces préparations sont décrites.

Affiliated with

Also associated with

Rating

Pharmaceutical preparation with factor viii procoagulant... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical preparation with factor viii procoagulant..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical preparation with factor viii procoagulant... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1420709