Pharmaceutical preparations

A - Human Necessities – 61 – K

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A61K 31/56 (2006.01) A61K 31/415 (2006.01) A61K 31/57 (2006.01)

Patent

CA 1188616

Abstract Topically applicable pharmaceutical preparation, containing a D-homosteroid of the formula Image I in which R6 signifies hydrogen, methyl, chlorine or fluorine, R9 signifies hydrogen, fluorine or chlorine, R11 sig- nifies oxo or (.alpha.-H,.beta.-OH), R17a signifies hydroxy or acyloxy, R20 signifies a group -O-R201 or -CH2 -R21, R201 signifies lower-alkyl, chloro-lower-alkyl or fluoro- -lower-alkyl, R21 signifies hydrogen, chlorine, fluorine, hydroxy or acyloxy and the dotted 1,2-bond signifies an optional C-C bond, and, where R20 is a group -O-R201, a double bond can be present in the 16,17-position, and a compound of the formula Image II in which R1 signifies hydrogen, halogen, lower-alkyl or lower-alkoxy and R2, R3 and R4 signify hydrogen, lower-alkoxy, hydroxy- -lower-alkoxy or two adjacent symbols R1, R2, R3 and R4 together signify methylene- dioxy, and at least one symbol R1, R2, R3 or R4 contains oxygen.

399814

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