Pharmaceutical preparations and methods for inhibiting tumors

Details Pharmaceutical preparations and methods for inhibiting tumors Pharmaceutical preparations and methods for inhibiting tumors

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 9/127 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 45/06 (2006.01) A61K 48/00 (2006.01) A61P 13/00 (2006.01) A61P 35/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2359650

The invention provides pharmaceutical compositions and method for inhibiting growth of prostatic adenocarcinoma, stomach cancer, breast cancer, endometrial, ovarian or other cancers of epithelial secretion, or benign prostate hyperplasia (BPH). In one embodiment the pharmaceutical composition includes human rHuPSP94, antigenic portions thereof, and functionally equivalent polypeptides thereof. In another embodiment, the pharmaceutical composition includes a mixture of human rHuPSP94, antigenic portions thereof, and functionally equivalent polypeptides thereof and an anticancer drug which may be administered in an appropriate dosage form, dosage quantity and dosage regimen to a patient suffering from, for example of prostatic adenocarcinoma, stomach cancer, breast cancer, endometrial, ovarian or other cancers of epithelial secretion, benign prostate hyperplasia, or (BPH) gastrointestinal cancer. The anticancer drug of the latter mixture may be one selected from the group of drugs including mitomycin, idarubicin, cisplatin, 5-fluoro- uracil, methotrexate, adriamycin, daunomycin, taxol, taxol derivative, and mixtures thereof.

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