Pharmaceutical preparations for oral administration and...

Details Pharmaceutical preparations for oral administration and... Pharmaceutical preparations for oral administration and...

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2238409

The invention concerns pharmaceutical preparations for oral administration in liquid-filled soft gelatin capsules. The preparations are charactacterized in that the active substance is dissolved in a single-phase system containing, in each case relative to the system free from active substance, between 1 and 20 wt.% pharmaceutically compatible polyols and/or benzyl alcohol, between 1 and 20 wt.% of one or a plurality of surfactants, between 79 and 98 wt.% of one or a plurality of co-surfactants, less than 5 wt.% ethanol and less than 10 wt.% water.

L'invention concerne des préparations pharmaceutiques pour administration par voie orale se présentant sous la forme de capsules de gélatine souple remplies de liquide. Les préparations présentées se caractérisent en ce que le principe actif est dissous dans un système monophase contenant, chaque fois par rapport au système exempt d'ingrédient actif, de 1 à 20 % en poids de polyols et/ou d'alcool benzylique pharmaceutiquement compatibles, de 1 à 20 % en poids d'un ou de plusieurs tensioactifs, de 79 à 98 % en poids d'un ou de plusieurs co-tensioactifs, moins de 5 % en poids d'éthanol et moins de 10 % en poids d'eau.

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