Pharmaceutical preparations for poorly-soluble active agents

A - Human Necessities – 61 – K

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Details

A61K 47/14 (2006.01) A61K 9/48 (2006.01) A61K 38/13 (2006.01) A61K 47/22 (2006.01) A61K 47/26 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2164100

The present invention relates to pharmaceutical preparations for poorly-soluble active agents, as well as processes for the production of these preparations. The solubilization agents employed are polyglycerol fatty acid esters or sorbitan fatty acid esters in combination with lipophilic excipients and non-ionic surfactants.

L'invention concerne des préparations pharmaceutiques pour principes actifs difficilement solubles, ainsi que des procédés permettant de produire ces préparations. On utilise comme agent de solubilisation des esters d'acide gras de polyglycérine ou des esters d'acide gras de sorbitanne en combinaison avec des additifs lipophiles et des tensioactifs non ioniques.

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