Pharmaceutical product

Details Pharmaceutical product Pharmaceutical product

A - Human Necessities

61

K

A61K 31/215 (2006.01) A61K 31/351 (2006.01) A61K 31/41 (2006.01) A61K 31/4192 (2006.01) A61K 31/428 (2006.01) A61K 45/00 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2649628

A TLR signaling inhibitor, preferably an inhibitor of the production of various cytokines such as IL-8 or an inflammatory mediator, an inhibitor of the expression of COX-II or the like or an inhibitor of various kinases such as ATF2 containing a compound represented by the formula (I) or the formula (II): (I) (II) (wherein the definition of each symbol is as described in the description), a salt thereof or a prodrug thereof.

L'invention concerne un inhibiteur d'un signal de TLR, de préférence un inhibiteur de la production de plusieurs cytokines telles que IL-8 ou un médiateur inflammatoire, un inhibiteur de l'expression de COX-II ou similaire, ou un inhibiteur de plusieurs kinases telles que ATF2 contenant un composé représenté par la formule (I) ou la formule (II): (I) (II) (la définition de chaque symbole étant telle que dans la description), un sel ou un promédicament de celui-ci.

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