A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
128/104, 128/60
A61M 31/00 (2006.01) A61K 9/70 (2006.01)
Patent
CA 1239318
A B S T R A C T The present invention is related to a pharmaceutical product preferably in medical bandage form, for the controlled release of a therapeutically active agent or several such agents to the skin. The pharmaceutical product of the invention consists of an impermeable backing layer, a parti- cularly composed supersaturated reservoir layer for the therapeutically active agent connected therewith and com- prising a polymer matrix wherein the therapeutically active agent is soluble and which is permeable to the active agent, an adhesive layer connected with the reservoir layer and permeable to said adhesive layer and removable therefrom for the use of the pharmaceutical product as transdermal therapeutic system, said reservoir layer for the therapeuti- cally active agent consisting of a multitude of layers wherein the concentration of the therapeutically active agent increases from layer to layer with increasing distance from the adhesive layer, and process for producing such a pharma- ceutical product.
451200
Hoffmann Hans R.
Meconi Reinhold
Wolff Michael
Zerbe Horst
Kirby Eades Gale Baker
Lohmann G.m.b.h. & Co. Kg
Schwarz (sanol) G.m.b.h.
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