A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) B01D 9/00 (2006.01) C07C 233/16 (2006.01)
Patent
CA 2443468
A pharmaceutical product comprising at least one therapeutic agent in crystalline form, said pharmaceutical product comprising at least one reticulated three-dimensional microstructure comprising: a network of substantially interconnecting walls, said walls being provided by a multiplicity of crystals arranged to at least partially abut each other; and a multiplicity of pores defined by said substantially interconnecting walls; wherein said therapeutic agent is characterised as having an aqueous solubility of not greater than about 1 in 30 to 1 in 100, weight/volume, when measured at a temperature in the range of 15 to 25~C.
La présente invention concerne un produit pharmaceutique comprenant au moins un agent thérapeutique. Une dose unitaire de cet agent thérapeutique prévue dans ce produit pharmaceutique peut être administrée à un patient pendant le passage de cet agent thérapeutique à travers le tractus gastro-intestinal de ce patient. Cet agent thérapeutique est caractérisé par le fait qu'il possède une solubilité aqueuse comprise environ entre 1 partie dans 30 poids/volume et 1 partie dans 100 poids/volume au maximum, lorsqu'on le mesure à une température comprise entre 15 ·C et 25 ·C.
Clinch Cheryl
Hearn Matthew Paul
Staniforth John Nicholas
Tobyn Michael John
Sim & Mcburney
Vectura Limited
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