Pharmaceutical salts of reboxetine

Details Pharmaceutical salts of reboxetine Pharmaceutical salts of reboxetine

C - Chemistry, Metallurgy

07

D

C07D 265/30 (2006.01) A61K 31/5375 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2489763

The present invention relates to novel crystalline, water-soluble salts of the 2S,3S enantiomer of reboxetine (Z-[-.alpha.-(2-ethoxy-phenoxy)-benzyl]-morpholine), which are the fumarate and succinate salts thereof, to a process for their preparation, to their utility in therapy and to pharmaceutical compositions containing them.

L'invention porte sur des nouveaux sels hydrosolubles et cristallins de 2S,3S énatiomère de reboxetine, qui sont des sels de fumarate et de succinate, et sur un procédé de préparation, sur leur utilisation thérapeutique et sur des compositions pharmaceutiques les contenant.

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