Pharmaceutical suspensions comprising phenylephrine and...

Details Pharmaceutical suspensions comprising phenylephrine and... Pharmaceutical suspensions comprising phenylephrine and...

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 31/137 (2006.01) A61K 31/167 (2006.01) A61K 31/4402 (2006.01) A61K 31/485 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2659382

A pharmaceutical suspension having a therapeutically effective amount of phenylephrine and a therapeutically effective amount of a first active agent consisting essentially of a first substantially water insoluble active agent having an average particle size of between about 10 and about 100 microns, an effective amount of non-reducing sweetener; an effective amount of water; and an effective amount of a suspending system; wherein the pharmaceutical suspension has a pH of from about 4 to about 6 and is substantially free of a reducing sugar and related methods.

L'invention porte sur une suspension pharmaceutique comprenant : une quantité thérapeutiquement efficace de phényléphrine et une quantité thérapeutiquement efficace d'un premier agent actif composé essentiellement d'un premier agent actif sensiblement insoluble dans l'eau possédant une taille de particule moyenne comprise entre environ 10 et environ 100 microns; une quantité efficace d'un édulcorant non réducteur; une quantité efficace d'eau; et une quantité efficace d'un système de suspension; la suspension pharmaceutique possédant un pH compris entre environ 4 et environ 6 et étant sensiblement dépourvue de sucre réducteur. L'invention concerne également des procédés associés.

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