A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 31/352 (2006.01) C07D 311/24 (2006.01)
Patent
CA 2312699
Cromoglycic acid compounds represented by general formula (I) which are advantageously usable in treating rheumatism, since they have antirheumatic, anti-inflammatory and immunomodulatory effects and are efficacious in controlling chronic rheumatoid arthritis symptoms while producing little side effects. Because of having antiallergic I and antiallergic IV activities, these compounds are advantageously usable in treating allergic dermatitides in which type IV allergic reaction participates, for example, contact dermatitis in which type IV allergic reaction participates mainly and atopic dermatitis in which both type I and type IV allergic reactions participate.
L'invention porte sur des composés de l'acide cromoglycique de formule générale (I) utilisables pour le traitement des rhumatismes en raison de leurs effets anti-rhumatismal, anti-inflammatoire, et immunomodulateur, et efficaces pour combattre les symptômes de la polyarthrite rhumatoïde chronique tout en ayant peu d'effets secondaires. En raison de leurs propriétés anti-allergiques I et IV, ils peuvent également traiter les dermatites allergiques associées aux réactions allergiques de type IV par exemple l'eczéma de contact dans lequel les réactions allergiques de type IV ont un rôle principal, ainsi que les dermatites atopiques liées aux réactions allergiques de type I et IV.
Fukata Fumio
Kanda Mamoru
Nakamura Shohei
Shirahase Hiroaki
Yoshimi Akihisa
Fetherstonhaugh & Co.
Kyoto Pharmaceutical Industries Ltd.
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