Pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydro-...

Details Pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydro-... Pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydro-...

C - Chemistry, Metallurgy

07

D

260/277.1, 260/2

C07D 221/08 (2006.01) C07D 401/02 (2006.01) C07D 401/12 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1200241

A B S T R A C T A 6- and/or 7-oxy-trans-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]- quinoline in which the 3-position is substituted by an optionally amidated carboxy group, an optionally etherified hydroxymethyl group, a cyanomethyl group, an alkyl- or aryl-thiomethyl group or a sulfamoylamino or carbamoylanlino group, or a physiologi- cally-hydrolysable and -acceptable ester thereof. The subject compounds are useful as pharmaceuticals, in, particular as prolac- tin secretion inhibitors, dopaminergic agents and dopamine re- ceptor stimulating agents.

413440

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