Pharmaceutically active compounds, their manufacture,...

Details Pharmaceutically active compounds, their manufacture,... Pharmaceutically active compounds, their manufacture,...

A - Human Necessities

61

K

A61K 33/24 (2006.01) A61K 33/26 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2597124

A substance for use as a medicament, comprises a solid mixed metal compound of formula (I): Mll 1-a Mlll aObAn- c.zH2O (I) where Mll is at least one bivalent metal: Mlll bis at least one trivalent metal; An- is at least one n-valent anion; 2+a = 2b+.SIGMA.cn; and .SIGMA.cn < 0.9a. The substance may be made by heating at a temperature of from 200~C to 600~C, preferably from 250~C to 500~C of a substance comprising a compound of formula (II): Mll 1-xMlll x(OH)2An- y.mH2O (II) where Mll is at least one bivalent metal; Mlll is at least one trivalent metal; An- is at least one n-valent anion; x = .SIGMA.yn 0 < x <= 0.5, 0 < y<= 1 and 0 <m <= 10.

Cette invention concerne une substance destinée à être utilisée comme médicament et comprenant un composé métallique mixte solide représenté par la formule (I) MII 1-aMIII aObAn- c.zH2O, dans laquelle MII désigne au moins un métal bivalent; MIII désigne au moins un métal trivalent; An- désigne au moins un anion de valence n; et 2+a = 2b+.SIGMA.cn et .SIGMA.cn < 0,9a. On peut obtenir cette substance en faisant chauffer, à une température comprise entre 200 et 600 °C, de préférence entre 250 et 500°C, une substance contenant un composé représenté par la formule (II) Mll 1-xMlll x(OH)2An- y.mH2O, dans laquelle MII désigne au moins un métal bivalent; MIII désigne au moins un métal trivalent; an- désigne au moins un anion à valence n; et x=.SIGMA.yn 0<x<=0,5, 0<y<=1 et 0<m<=10.

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