Pharmaceutically active cyclohexyl compounds and their...

A - Human Necessities – 61 – K

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167/263, 167/269

A61K 31/16 (2006.01) A61K 31/19 (2006.01) C07C 51/08 (2006.01) C07C 51/09 (2006.01) C07C 51/27 (2006.01) C07C 51/353 (2006.01) C07C 51/367 (2006.01) C07C 51/377 (2006.01) C07C 51/41 (2006.01) C07C 51/60 (2006.01) C07C 61/08 (2006.01) C07C 61/15 (2006.01) C07C 61/35 (2006.01) C07C 61/39 (2006.01) C07C 61/40 (2006.01) C07C 62/04 (2006.01) C07C 62/10 (2006.01) C07C 62/20 (2006.01) C07C 62/34 (2006.01)

Patent

CA 1150150

ABSTRACT OF THE DISCLOSURE The chemical compounds of the invention are useful as the active compound in drugs because of their anticonvul- sivant and/or antianoxic activity. They have the general formula Image wherein Z is a hydroxyl group; a group -OM wherein M is an alkali metal atom or an equivalent atom fraction of an alka- line-earth metal or an amino group such as -NH2, and R is a linear or branched alkyl group containing from 1 to 9 carbon atoms, and optionally substituted by one or more halogen atoms; a linear or branched alkenyl or alkynyl, alkoxyalkyl, or acylalkyl group containing from 2 to 9 carbon atoms and optionally substituted by one or more halogen atoms; an aryl or arylalkyl or aryloxyalkyl group comprising at least one aromatic radical and an alkyl chain having from 1 to 4 car- bon atoms.

326456

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