Pharmaceutically active morpholinol

Details Pharmaceutically active morpholinol Pharmaceutically active morpholinol

C - Chemistry, Metallurgy

07

D

C07D 265/32 (2006.01) A61K 31/535 (2006.01) A61K 31/5375 (2006.01)

Patent

CA 2318268

Disclosed is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2- morpholinol and pharmaceutically acceptable salts and solvates thereof, pharmaceutical compositions comprising them; also disclosed is a method of treating depression, attention deficit hyperactivity disorder (ADHD), obesity, migraine, pain, sexual dysfunction, Parkinson's disease, Alzheimer's disease, or addiction to cocaine or nicotine-containing (especially tobacco) products using such compound, salts, solvates or compositions.

La présente invention concerne le composé (+)-(2S,3S)-2-(3-chlorophényle)-3,5,5-triméthyle-2-morpholinol, les sels et les solvats pharmaceutiquement acceptables de ce composé ainsi que des compositions renfermant lesdites substances. L'invention concerne également une méthode de traitement, au moyen desdits composés, sels, solvats et compositions, de la dépression, des troubles de l'hyperactivité avec déficit de l'attention, de l'obésité, de la migraine, de la douleur, des dysfonctionnements sexuels, de la maladie de Parkinson, de la maladie d'Alzheimer et de la dépendance à la cocaïne ou aux produits renfermant de la nicotine (en particulier le tabac).

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