C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/119, 260/428
C07F 15/00 (2006.01) A61K 31/285 (2006.01) A61K 31/66 (2006.01) C07F 15/02 (2006.01) C07F 15/04 (2006.01) C07F 15/06 (2006.01)
Patent
CA 1269395
ABSTRACT Novel bis[bis(diphenylphosphino)hydrocarbon] and bis[diphenylphosphino-diphenylarsino)hydrcarbon]-group VIII metal campounds of the formula 1 of the fonmula sheet, wherein D1 = D2 = phosphorus or D1 = phosphorus and D2 = arsenic; A = (CH2)2 or cis-CH = CH; X1 = X2 (both if present) = halo or nitrato or X1 + X = peroxo; Y (if present) = halide, nitrate, perchlorate, triflate or tetrahaloferrate (III); n = 0, 1 or 2; M = Fe(II), Fe(III), Co(II), Rh(I), Rh(III), Ir(I), Ir(III), Ni(II) or Pd(II), showing a tumor cell growth-inhibiting activity, novel pharmaceutical compositions containing said compounds and a method for treating tumor cells, sensitive to said compounds.
521403
Meinema Harmen A.
Schurig John E.
Timmer Klaas
Meinema Harmen A.
Nederlandse Centrale Organisatie Voor Toegepast- Natuurwetenscha
Ridout & Maybee Llp
Schurig John E.
Timmer Klaas
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