Pharmaceuticals

Details Pharmaceuticals Pharmaceuticals

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/535 (2006.01) C07D 209/00 (2006.01) C07D 265/00 (2006.01)

Patent

CA 2312844

Novel oxazino[3,2-a]indole-10-carboxamide derivatives having 5-HT4 receptor antagonist activity and useful in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders, including irritable bowel syndrome.

L'invention concerne de nouveaux dérivés d'oxazino[3,2-a]indole-10-carboxamide qui ont une activité d'antagonistes des récepteurs de 5-HT¿4? et sont utiles pour le traitement de troubles gastro-intestinaux ou vasculaires et de troubles du S.N.C., y compris le syndrome du côlon irritable.

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