C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/00 (2006.01) C07D 473/40 (2006.01)
Patent
CA 2101640
A process for preparing 2-amino-6-chloropurine or a 2-acylated derivative thereof, comprising reacting guanine or 2,9-dia- cylguanine with a chlorinating agent, in the presence of methyltriethylammonium chloride as phase transfer catalyst, and thereaf- ter when necessary, removing the 9-acyl group by hydrolysis.
Fetherstonhaugh & Co.
Novartis International Pharmaceutical Ltd.
Smithkline Beecham P.l.c.
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