Pharmaceuticals, phosphorus-containing 2-isoxazolines and...

Details Pharmaceuticals, phosphorus-containing 2-isoxazolines and... Pharmaceuticals, phosphorus-containing 2-isoxazolines and...

C - Chemistry, Metallurgy

07

F

167/208, 260/302

C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/653 (2006.01)

Patent

CA 1329604

- 1 - ABSTRACT OF THE DISCLOSURE Pharmaceuticals, phosphorus-containing 2-isoxazolines and isoxazoles contained therein, and processes for the preparation of these heterocyclic compounds Pharmaceuticals containing or composed of at least one compound of the formula I and/or one of its physiologi- cally tolerated salts where appropriate, where the compounds of the formula I can, where appropriate, be in the form of pure stereoisomers or mixtures thereof; formula I is: Image (I) in which R1 = organic radical or halogen, A = C,C single or C,C double bond, n = 0, 1 or 2, and X and Y = alkyl radical or = -OR2 or -NR2R3 with R2 and R3 = H or optionally substituted aliphatic radical. The pharmaceuticals are suitable for the prophylaxis and/or treatment of diseases of the immune system, especially of tumors, infections and/or autoimmune diseases of the human or animal body and for use as adjuvants for vaccines. Some of the compounds of the formula I are new; the compounds can be prepared by special processes.

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