Pharmacological agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 217/06 (2006.01) A61K 31/00 (2006.01) A61K 31/47 (2006.01) A61K 31/4725 (2006.01) C07D 217/26 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2285192

Antagonists selective for the GluR5 receptor are useful for the treatment of pain. Also disclosed are novel decahydroisoquinoline derivatives which are selective GluR5 receptor antagonists.

L'invention a trait à des antagonistes ayant une affinité élective pour le récepteur GluR5 qui s'avèrent efficaces en tant qu'analgésiques. Elle concerne également de nouveaux dérivés de décahydroisoquinoléine ayant une affinité élective pour des antagonistes du récepteur GluR5.

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