Pharmacologically active 5-oxo-1 imidazoldine acetamide...

Details Pharmacologically active 5-oxo-1 imidazoldine acetamide... Pharmacologically active 5-oxo-1 imidazoldine acetamide...

C - Chemistry, Metallurgy

07

K

530/5.04, 260/31

C07K 5/04 (2006.01) C07D 233/38 (2006.01) C07K 5/00 (2006.01)

Patent

CA 1271598

ABSTRACT PHARMACOLOGICALLY ACTIVE COMPOUNDS Compounds of Structure (1) Image (1) in which R1 is H, C1-5 alkyl (straight or branched), or a phenyl or benzyl group optionally substituted by C alkyl (???aight or branched), C alkoxy 1-4 (straight or branched) or hydroxy; R2 is H, OH, C1-5 alkyl (straight or branched), aryl or acyl; R3 is H, C1-5 alkyl (straight or branched) or phenyl and R4 is C1-5 alkyl (straight or branched) or phenyl, or R3 and R4 can together form a 1,4-butylene or 1,5-pentylene group; R5 is H or C1-5 alkyl (straight or branched); R6 is H, C1-5 alkyl (straight or branched), -CHR8CONH2 or -CHR8CONCHR9CONH2; where R8 and R9 (which can be the same or different) are H or C1-5 alkyl (straight or branched); and R7 is H or C1-5 alkyl (straight or branched), and pharmaceutically acceptable salts thereof, processes and intermediates for making them, pharmaceutical compositions containing them and their use as nootropic agents.

512115

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