Pharmacologically active cns compounds

Details Pharmacologically active cns compounds Pharmacologically active cns compounds

C - Chemistry, Metallurgy

07

D

C07D 253/075 (2006.01) A61K 31/53 (2006.01)

Patent

CA 2043642

ABSTRACT PHARMACOLOGICALLY ACTIVE CNS COMPOUNDS The invention provides compounds of formula (I) Image wherein at least one of R1, R2 and R3 is chloro and the others are selected from hydrogen and chloro; and R4 and R5 are the same or different and are each alkyl or hydrogen. The compounds may be used for the treatment or prophylaxis of a neurodegenerative of other neurological disorder of the CNS, the aetiology of which includes excessive release of the neurotransmitter glutamate. PA1155/ABS

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