Pharmacologically active guanidine derivatives

Details Pharmacologically active guanidine derivatives Pharmacologically active guanidine derivatives

C - Chemistry, Metallurgy

07

D

260/295, 260/302

C07D 233/64 (2006.01) C07C 281/18 (2006.01) C07D 213/32 (2006.01) C07D 233/54 (2006.01) C07D 277/22 (2006.01) C07D 277/26 (2006.01) C07D 277/28 (2006.01)

Patent

CA 1076579

ABSTRACT OF THE DISCLOSURE Compounds are disclosed of the formula: Image where R1 represents the structure Het-(CH2)mZ(CH2)n- where Het is an imidazolyl, thiazolyl or pyridyl ring, which ring may be optionally substituted by a C1-C4 alkyl group, a chlorine atom or a bromine atom Z is sulphur or methylene m is 0, 1 or 2 n is 2 or 3 provided that the sum of m and n is 3 or 4z R2 is a C1-C4 alkyl group or the structure Het-(CH2)mZ(CH2)n- X is oxygen or NH and R3 is hydrogen, a C1-C4 alkyl group or phenyl. The compounds are histamine H2-antagonists and find use as inhibitors of gastric acid secretion, or anti-inflammatory agents.

229222

Affiliated with

Also associated with

Rating

Pharmacologically active guanidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmacologically active guanidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmacologically active guanidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-498528