Pharmacologically active isothioureas derivatives

Details Pharmacologically active isothioureas derivatives Pharmacologically active isothioureas derivatives

C - Chemistry, Metallurgy

07

D

260/466.05

C07D 233/96 (2006.01) C07C 335/32 (2006.01)

Patent

CA 1083171

ABSTRACT OF THE DISCLOSURE Compounds of the formula: Image wherein n is an integer from 3 to 6, R is lower alkyl or Image , X is sulphur, NCN or CHNO2 are disclosed. The compounds are useful as histamine H2-antagonists and act, for example, as inhibitors of gastric acid secretion and anti-inflammatory agents.

266796

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