Pharmacologically active n-butylamine derivatives and...

Details Pharmacologically active n-butylamine derivatives and... Pharmacologically active n-butylamine derivatives and...

C - Chemistry, Metallurgy

07

C

260/609.5

C07C 53/128 (2006.01) A61K 31/13 (2006.01) C07C 29/42 (2006.01) C07C 51/08 (2006.01) C07C 51/353 (2006.01)

Patent

CA 1048549

ABSTRACT OF THE DISCLOSURE: n-Butylamine derivatives having the general formula: Image (I) and the pharmaceutically acceptable acid addition salts thereof, wherein R1 represents ethyl or n-propyl and R2 represents (a) ethyl, n-propyl, isopropyl, isobutyl or tert-butyl when R1 is n-propyl and (b) n-butyl or isobutyl when R1 is ethyl, with the proviso that R1 and R2 simultaneously represent n-propyl only when the derivative is in the form of its acid fumarate, possess valuable pharmacological properties which are likely to render them useful in the treatment of Parkinson's disease and the correction of extra-pyramidal disturbances provoked by neuroleptics.

227044

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