Pharmacologically active peptide conjugates having a reduced...

C - Chemistry – Metallurgy – 07 – K

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C07K 1/107 (2006.01) A61K 47/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2321026

The invention is directed to a pharmacologically active peptide conjugate having a reduced tendency towards enzymatic cleavage comprising a pharmacologically active peptide sequence (X) and a stabilising peptide sequence (Z) of 4-20 amino acid residues covalently bound to X.

L'invention concerne un conjugué peptidique pharmacologiquement actif ayant une tendance réduite au clivage enzymatique, comportant une séquence peptidique pharmacologiquement active (X) et une séquence peptidique stabilisatrice (Z) de 4 à 20 restes d'acides aminés liés par covalence à X.

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