Pharmacophore recombination for the identification of small...

C - Chemistry – Metallurgy – 40 – B

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Details

C40B 40/04 (2006.01) C07C 321/12 (2006.01) C40B 30/04 (2006.01) C40B 80/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2326341

The disclosure is directed to methods of identifying drug leads or binding compounds which have affinity for a target molecule by cross-linking members of a library of potential target binding molecules and screening the crosslinked complexes.

L'invention a trait à des procédés d'identification de pistes utiles pour la recherche de médicaments ou de composés de liaison qui présentent une affinité pour une molécule cible, par la mise en oeuvre d'une réticulation d'éléments d'une bibliothèque de molécules de liaison cibles potentielles et d'un criblage des complexes réticulés.

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