Phase sensitive differential polarimetry technique and...

Details Phase sensitive differential polarimetry technique and... Phase sensitive differential polarimetry technique and...

C - Chemistry, Metallurgy

12

M

C12M 1/34 (2006.01) C12M 1/40 (2006.01) G01J 4/04 (2006.01) G01N 21/21 (2006.01) G01N 21/75 (2006.01)

Patent

CA 2076033

A differential polarimeter is disclosed for detecting changes in optical rotation between a test cell and reference cell. The test cell contains a fluid sample exposed to an analyte specific enzyme; the reference cell contains a fluid sample not exposed to the enzyme. To enhance the sensitivity of the system a phase sensitive differential polarimetric technique is taught. In this technique, the phase difference between two resulting sinewave voltages is a measure of analyte concentration.

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