C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/14 (2006.01) C07C 49/755 (2006.01) C07D 307/92 (2006.01) C12P 7/22 (2006.01) C12P 17/04 (2006.01)
Patent
CA 2476618
The invention relates to phenalenone derivatives, to the production of the same, whereby the micro-organism Penicillium herquei Bainer & Sartory, DSM 14142, is fermented and the phenalones formed during said fermentation are derivatized, and to the use of said phenalenone derivatives as medicaments, especially for fighting tumour diseases, bacterial infections and/or mycoses and rheumatic diseases.
L'invention concerne des dérivés de phénalénone et leur production par fermentation du micro-organisme Penicillium herquei Bainer & Sartory, DSM 14142, ainsi que par dérivatisation des phénalénones obtenues pendant la fermentation. L'invention concerne également l'utilisation de ces dérivés de phénalénone comme médicaments, par exemple pour le traitement de maladies tumorales, d'infections ou de mycoses bactériennes et d'affections rhumatismales.
Kurz Michael
Li Ziyu
Toti Luigi
Vertesy Laszlo
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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