Phenanthridine derivatives, methods of producing them and...

C - Chemistry – Metallurgy – 07 – D

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C07D 221/18 (2006.01) A61K 31/47 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07J 73/00 (2006.01)

Patent

CA 2232609

Disclosed are novel phenanthridine derivatives of general formulae (I) and (II) and the salts thereof. In the formulae, R1 is a hydrogen atom or aromatic carbocyclic or heterocyclic group, and R2 and R3 can be either identical or different and stand for a hydrogen atom, an alkyloxy group, an alkylene-oxy group, a halogen atom or a nitro group. The derivatives in question have anti- tumoral, anti-microbial, fungicidal, anti-viral and anti-inflammatory properties.

L'invention concerne de nouveaux dérivés de phénanthridine des formules générales (I) et (II), ainsi que leurs sels. Dans lesdites formules, R¿1? désigne un atome d'hydrogène, un reste carbocyclique ou hétérocyclique aromatique, et R¿2? et R¿3?, qui peuvent être identiques ou différents, désignent un atome d'hydrogène, un reste alkyloxy, un reste alkylènoxy, un atome d'halogène ou un groupe nitro. Ces dérivés de phénanthridine présentent des propriétés antitumorales, antimicrobiennes, antifongiques, antivirales et anti-inflammatoires.

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