Phenanthroline-7-one derivatives and their therapeutic uses

Details Phenanthroline-7-one derivatives and their therapeutic uses Phenanthroline-7-one derivatives and their therapeutic uses

C - Chemistry, Metallurgy

07

D

C07D 471/16 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01)

Patent

CA 2381352

The invention concerns a pharmaceutical composition comprising an efficient amount of a compound selected among the compounds of formulae (I) and (Ia), wherein: R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6? and R¿7? are as defined in Claim 1. Said compounds have interesting cytotoxic properties leading to a therapeutic use as antitumoral medicines.

La présente invention concerne une composition pharmaceutique comprenant une quantité efficace d'un composé choisi parmi les composés de formule (I) et (Ia), dans lesquelles, R1, R2, R3, R4, R5, R6 et R7 sont tels que définis à la revendication 1. Ces composés possèdent des propriétés cytotoxiques intéressantes conduisant à une application thérapeutique comme médicaments anti-tumoraux.

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