Phenethylamine derivatives

Details Phenethylamine derivatives Phenethylamine derivatives

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/087 (2006.01) C07K 5/09 (2006.01) C07K 5/093 (2006.01) C07K 5/097 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2301687

Compounds represented by general formula (1) which are phenethylamine derivatives exhibiting a motilin receptor antagonism etc. and being useful as drugs, wherein A represents an amino acid residue, etc.; R1 represents R6-CO-, etc.; R2 represents hydrogen, etc.; R3 represents -CO-R7, etc.; R4 represents alkyl, etc.; R5 represents hydroxy, etc.; R6 represents alkyl, etc.; and R7 represents amino, etc.

La présente invention concerne des composés représentés par la formule générale, en l'occurrence des dérivés de phényléthylamine présentant entre autres une activité antagoniste au récepteur de la motiline. Dans cette formule générale (I), A est notamment radical d'acide aminé; R¿1? est notamment R¿6?-CO-; R¿2? est notamment hydrogène; R¿3? est notamment -CO-R¿7?; R¿4? est notamment alkyle; R¿5? est notamment hydroxy; R¿6? est notamment alkyle; et R¿7? est notamment une amine.

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