Phenethylamine derivatives and intermediates therefor

Details Phenethylamine derivatives and intermediates therefor Phenethylamine derivatives and intermediates therefor

A - Human Necessities

61

K

260/353, 260/557

A61K 31/135 (2006.01)

Patent

CA 1248540

PHENETHYLAMINE DERIVATIVES Abstract of the Disclosure This invention provides a group of hydroxycycloalkanephenethyl amine antidepressant derivatives of the following structural formula: Image in which A is a moiety of the formula Image where the dotted line represents optional unsaturation; R1 is hydrogen or alkyl; R2 is alkyl; R4 is hydrogen, alkyl, formyl or alkanoyl; R5 and R6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl or, taken together, methylenedioxy; R7 is hydrogen or alkyl; and n is 0, 1, 2, 3 or 4; or a pharmaceutically acceptable salt thereof.

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